RP-HPLC method for simultaneous estimation of nitazoxanide and ofloxacin in tablets
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RP-HPLC Method for Simultaneous Estimation of Nitazoxanide and Ofloxacin in Tablets
A reverse phase high performance liquid chromatography method was developed for simultaneous estimation of nitazoxanide and ofloxacin in tablet formulation. The separation and quantification was achieved by Hiq Sil C(18)V Size 4.6 mm Ø (*)250 mm column in isocratic mode, with mobile phase consisting of acetonitrile-methanol-0.4 M citric acid, (60:30:10, v/v/v). Citric acid used to stabilize nit...
متن کاملRP-HPLC methods for estimation of Nitazoxanide single and simultaneous estimation of Nitazoxanide with Ofloxacin in pharmaceutical dosage forms
Two simple, selective, rapid, precise and economical reverse phase high-pressure liquid chromatography methods have been developed; first method for estimation of nitazoxanide and second method for simultaneous estimation of nitazoxanide & ofloxacin from pharmaceutical dosage forms. The first method carried out on a Hypersil BDS C8 column (5μ particles size) (250 mm X 4.6 mm), with mobile phase...
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ژورنال
عنوان ژورنال: Indian Journal of Pharmaceutical Sciences
سال: 2011
ISSN: 0250-474X
DOI: 10.4103/0250-474x.89763